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Colorectal Cancer Panel
MAHS Colon Cancer Panel Assay
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86 mutations
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BRAF, EGFR, KRAS, NRAS, PIK3CA
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BRAF
G469E, D594G, V600E
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EGFR
S492R
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KRAS
G12A/C/D/E/F/I/L/R/S/V/W/Y, G13A/C/D/E/F/R/S/V, A59E/G/S/T, Q61E/H/K/L/P/R, K117N/R, A146G/P/T/V
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NRAS
G12A/C/D/R/S/V, G13A/C/D/R/S/V, A59G/T, Q61E/H/K/L/P/R, K117E/N/R, A146G/P/S/T/V
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PIK3CA
E542K, E545K, H1047L, H1047R
Specimen Requirements
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FFPE tissue section in tube 2 X 5 µm, at least > 20% tumor cell percentage of FFPE section: If below standards -> macro-dissection needed
LAT (Laboratory turnaround time)
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5-10 days
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