Colorectal Cancer Panel

MAHS Colon Cancer Panel Assay
 

• 86 mutations

• BRAF, EGFR, KRAS, NRAS, PIK3CA

1. BRAF

   G469E, D594G, V600E

2. EGFR

   S492R

3. KRAS

   G12A/C/D/E/F/I/L/R/S/V/W/Y, G13A/C/D/E/F/R/S/V, A59E/G/S/T, Q61E/H/K/L/P/R, K117N/R, A146G/P/T/V

4. NRAS

   G12A/C/D/R/S/V, G13A/C/D/R/S/V, A59G/T, Q61E/H/K/L/P/R, K117E/N/R, A146G/P/S/T/V

5. PIK3CA

E542K, E545K, H1047L, H1047R

Specimen Requirements

• FFPE tissue section in tube 2 X 5 µm, at least > 20% tumor cell percentage of FFPE section: If below standards -> macro-dissection needed
   

LAT (Laboratory turnaround time)

• 5-10 days