Microscope

Lung Cancer Panel

MAHS Lung & Lung Cancer Fusion Panel Assay
 

  • 70 mutations + 3 fusion genes

  • Mutation genes: BRAF, EGFR, ERBB2, KRAS, PIK3CA

  • Fusion genes: ALK, RET, ROS1

  • Mutations:

  1. BRAF

    G469A/V, D594G, V600E

  2. EGFR

    E709A/G/K/V, G719A/C/D/S, S768I/N/T, D770N, T790M, C797S, L858R, L861QR, exon 19 insertion/deletion, exon 20 insertion

  3. ERBB2

    Exon 20 insertions

  4. KRAS

    G12A/C/D/R/S/V, G13V/C/D, Q61E/H/K/L/P/R

  5. PIK3CA
     

E542K, E545K, H1047L, H1047R

  • Fusion genes:

  1. ALK

  2. RET

  3. ROS1

Specimen Requirements

  • FFPE tissue section in tube 2 X 10 µm, at least > 40% tumor cell percentage of FFPE section: If below standards -> macro-dissection needed
     

LAT (Laboratory turnaround time)

  • 5-10 days

MAHS Lung Cancer Panel Assay
 

  • 70 mutations

  • Mutation genes: BRAF, EGFR, ERBB2, KRAS, PIK3CA

  1. BRAF

    G469A/V, D594G, V600E

  2. EGFR

    E709A/G/K/V, G719A/C/D/S, S768I/N/T, D770N, T790M, C797S, L858R, L861QR, exon 19 insertion/deletion, exon 20 insertion

  3. ERBB2

    Exon 20 insertions

  4. KRAS

    G12A/C/D/R/S/V, G13V/C/D, Q61E/H/K/L/P/R

  5. PIK3CA
     

E542K, E545K, H1047L, H1047R

Specimen Requirements

  • FFPE tissue section in tube 2 X 5 µm, at least > 20% tumor cell percentage of FFPE section: If below standards -> macro-dissection needed
     

LAT (Laboratory turnaround time)

  • 5-10 days

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MAHS Lung Fusion Cancer Panel Assay
 

  • 3 fusion genes

  • Fusion genes: ALK, RET, ROS1

  1. ALK

  2. RET

  3. ROS

Specimen Requirements

  • FFPE tissue section in tube  2 X 10 µm, at least > 40% tumor cell percentage of FFPE section: If below standards -> macro-dissection needed
     

LAT (Laboratory turnaround time)

  • 5-10 days

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