Oncology Panels
MAHS Lung Cancer & Lung Fusion Panel Assay
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70 mutations & 3 fusion genes
Mutations
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BRAF | G469A/V, D594G, V600E
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EGFR |E709A/G/K/V, G719A/C/D/S, S768I/N/T, D770N, T790M, C797S, L858R, L861QR, exon 19 insertion/deletion, exon 20 insertion
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ERBB2 | Exon 20 insertions
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KRAS |G12A/C/D/R/S/V, G13V/C/D, Q61E/H/K/L/P/R
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PIK3CA | E542K, E545K, H1047L, H1047R
Fusion genes
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ALK
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RET
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ROS1
Specimen Requirements
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FFPE tissue selection in tube 2x 10µm, at least >40% tumor cell percentage of FFPE section. If below standards: macro dissection needed
LAT (Laboratory turnaround time)
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10 - 14 working days
MAHS Lung Cancer Panel Assay
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70 mutations & 3 fusion genes
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BRAF | G469E, D594G, V600E
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EGFR |E709A/G/K/V, G719A/C/D/S, S768I/N/T, D770N, T790M, C797S, L858R, L861QR, exon 19 insertion/deletion, exon 20 insertion
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ERBB2 | Exon 20 insertions
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KRAS |G12A/C/D/R/S/V, G13V/C/D, Q61E/H/K/L/P/R
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PIK3CA | E542K, E545K, H1047L, H1047R
Specimen Requirements
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FFPE tissue selection in tube 2x 10µm, at least >20% tumor cell percentage of FFPE section. If below standards: macro dissection needed
LAT (Laboratory turnaround time)
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10 - 14 working days
MAHS Lung Fusion Cancer Panel Assay
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3 fusion genes
Fusion genes
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ALK
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RET
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R0S1
Specimen Requirements
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FFPE tissue selection in tube 2x 10µm, at least >40% tumor cell percentage of FFPE section. If below standards: macro dissection needed
LAT (Laboratory turnaround time)
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10 - 14 working days
MAHS Colon Cancer Panel Assay
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86 mutations
Mutations
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BRAF | G469E, D594G, V600E
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EGFR | S492R
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KRAS G12A/C/D/E/F/I/L/R/S/V/W/Y,G13A/C/D/E/F/R/S/V, A59E/G/S/T, Q61E/H/K/L/P/R, K117N/R, A146G/P/T/V
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NRAS | G12A/C/D/R/S/V, G13A/C/D/R/S/V, A59G/T, Q61E/H/K/L/P/R, K117E/N/R,
A146G/P/S/T/V -
PIK3CA | E542K, E545K, H1047L, H1047R
Specimen Requirements
-
FFPE tissue selection in tube 2x 10µm, at least >40% tumor cell percentage of FFPE section. If below standards: macro dissection needed
LAT (Laboratory turnaround time)
-
10 - 14 working days